In accordance with our vision, having established a sound service delivery program conforming to the highest quality standards, we at ISIC are focusing our attention on education and research. To this end, our doctors and researchers have undertaken several clinical research projects. Our aim is to develop a facility which would provide a platform for basic researchers to interact closely with clinicians with a mission to provide cutting-edge solutions to existing therapeutic loopholes in medical science. Efforts to this effect are reflected in the following completed/ongoing clinical research projects undertaken at ISIC.
Director General’s Message: “I have been in this field for the past forty years. It breaks my heart that with the best technology at my disposal, I cannot tell a patient that he/she will walk again. Now, for the first time, we can see a ray of hope. There is a tremendous promise in stem cell research. We have to uncover the secrets and give them to humanity as a gift. Tomorrow’s world is a stem-cell world.”
Dr. A.K. Mukherjee
Dr. Chhabra has diverse research interest related with Spinal Cord Injury including injury prevention and care, developing novel ways to prevent or cure the disease and establish methods for better inclusion of spinal injured into the community. He has authored multiple journal articles, helped ISCoS in publishing a textbook on ‘Comprehensive Management of Spinal Cord Injuries’ as Editor in Chief, and developed elearnSCI.org, an online learning web based portal for health professionals and consumers on comprehensive management of Spinal Cord Injuries.
Dr. Phadke is a physiotherapist with doctorate in Rehabilitation Sciences from University of Minnesota, USA. Her research interests are related to kinematic analysis of human movement and exercise prescription. She has established a motion analysis lab at ISIC and leads a DST funded study on chronic low back pain patients. She is a recognized PhD mentor for physiotherapy at GGSIPU, Delhi.
Dr. Nagpal is doctorate from National Institute of Immunology,Delhi. She has earned her Masters in Biotechnology from BITS Pilani and Bachelors in Pharmacy from IIT BHU. Her research interests include Platelet rich plasma therapy, Pressure Ulcer treatment, Nerve Regeneration for SCI treatment, Polymer scaffolds and conduit for three dimensional Organ culture and Molecular diagnostic Marker.
Dr. Goel is an Orthopaedic-Spine surgeon. He did his fellowship in surgical & translational research at University of Wisconsin, Madison, USA, fellowship in spine from University of Colorado, USA and AO spine Fellowship from ISIC. His research interests include developing novel methods for cure of paralysed patients, skill development and disease management in rural India using tele-medicine and new animal model development for spinal research.
Ms. Sharawat is a Senior Research Associate at ISIC. Her research area in spinal cord injuries include epidemiology, prevention and use of alternative medicine such as meditation. She has been instrumental in developing and maintaining international registries for spinal cord injury and fracture care such as EMSCI, IDAPP, INORMUS. She has published journal articles and book chapters in the field of SCI management.
The following research projects are currently being undertaken at ISIC :
To achieve the aim of an integrated therapeutic and research facility, ISIC is setting up a Basic Research facility as well as an Animal House at Indian Spinal Injuries Centre (New Delhi, India) for the Development of Cell-Based Therapies for Spinal Cord Injury Repair
This research facility will include a Mammalian Cell Culture Room, Molecular Biology Lab and will be supported by a well established Animal House.
The role of the Basic Research Facility is to promote and facilitate the use of cell culture as a research tool and provide support to clinicians to study disease progression as well as effect of treatment at the molecular level. This facility will include a cell culture room comprising of state-of-art equipment required for establishment and maintenance of mesenchymal stem cells cell lines as well as primary mammalian cell cultures such as laminar flow hood, CO2 incubators, light phase dissecting microscope, a routine phase contrast microscope, etc. In addition to this, a separate imaging area consisting of a fluorescence microscope with imaging facility will also be provided for immuno-fluorescence studies on cultured cells. Proper areas will be developed in the facility to facilitate culture media preparation, testing and screening, culturing of primary cells and established cell lines as well as their long-term preservation. Infrastructure to undertake advanced molecular and immunological analyses will also be developed.
Along with basic research, ISIC is committed to providing cutting edge treatments to our patients. To this end, a STEM CELL PROCESSING UNIT has been established at ISIC and a clinical trial on the efficacy of stem cell therapy in case of acute spinal injury is going to be initiated shortly by our team of clinicians and researchers.